With its unique ability to mitigate the consequences of oxidative stress A1M represents a promising drug candidate. Preclinical studies suggest that it could be used to protect and repair the body’s tissues in, amongst other conditions, preeclampsia and renal failure.

Against the background of what we know today, it’s possible that A1M may constitute a therapeutic or diagnostic tool for a number of different conditions and illnesses. Not least, it could be used to stem the degradative processes associated with various types of inflammatory conditions in which oxidative stress has been induced by a variety of causes.

In our current research the main focus is on the treatment of pre-eclampsia, with a secondary focus on renal damage.

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Åkerström & Gram:
A1M, an extravascular tissue cleaning and housekeeping protein (Free Radical Biology and Medicine 2014)